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For example, the chelate formed by ethylenediaminetetraacetic acid (EDTA) with metal ions is tens of thousands of times more stable than that of ammonia, because the chelate ring structure reduces the competitive coordination of solvent molecules and lowers the entropy change of hydration of metal ions

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Several human studies show that supplemental carnitine can raise plasma TMAO in some individuals

described a 42-month-old female with microcephaly, developmental delay, and moderately low carnitine levels who had a homozygous 221 Kb deletion in 11p14.2, which includes BBOX1 , but investigations to validate the biochemical phenotype were not performed 8

Anti-ageing benefits: Combats oxidative stress that accelerates ageing, protects against free radical damage, and promotes tissue repair and renewal for healthier, more youthful cells