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The digestive side effects can be significant enough that some patients decide to stop the medication
10.1055/s-2004-835835 132 MikiM.AtutoshiK.YutakaM.KazumiY
Your provider may discuss medication combinations, switching to a different agent, or focusing intensively on the lifestyle factors that amplify tirzepatide's effects
When to Talk to your Doctor Persistent fatigue that doesnt improve could signal that something else is going on like: Iron or B12 deficiency (especially if your intake has dropped) Low thyroid levels Blood sugar fluctuations Ask your healthcare provider to check relevant labs, and discuss whether your semaglutide dose or titration schedule should be adjusted
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