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GHS-R1a Receptor Activation GH Axis Biology GHRP-6 activates GHS-R1a via phospholipase C/diacylglycerol/PKC signalling, mobilising intracellular calcium in anterior pituitary somatotrophs to trigger GH vesicle fusion and exocytosis

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The dithiol mechanism was too slow to compete with the monothiol mechanism in the presence of GSH or GSSG and was only detected for the oxidation of roGFP2 using diamide-treated PfGrx without GSH

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