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However, while a few clinical studies have reported small changes in thyroid levels in participants with hypothyroidism on who are on thyroid replacement therapy while taking PPIs, a clear connection has not been firmly established

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Key Signs That Warrant a Doctor Visit You should schedule an appointment with a board-certified doctor if you experience any of the following with your facial spots: Rapid Changes: A spot that changes significantly in size, shape, or color over a few weeks or months

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However, the best option depends on your health, medical history, and treatment goals