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It is handed between proteins in a thermodynamic hierarchy, and the relevant partners named in the GHK literature include serum albumin, which has a dedicated high-affinity N-terminal site, ceruloplasmin as the dominant circulating copper protein, metallothioneins as high-capacity intracellular sinks, and cuproenzymes that require the metal to function

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The ratio of intracellular GSSG/GSH was obviously elevated after MCF-7 and HeLa cells were treated with TeNWs (Figure 1I)

Mean Elimination Half-Life (t): In rats, the average elimination half-life after a single intravenous (IV) administration is 15.2 minutes