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Hyperpigmentation happens when small areas of skin make too much melanin, forming age spots, melasma, or postinflammatory marks
Chien PFW, Smith K, Peter WW, Scrimgeour CM, Talor DJ, Rennie MJ: Protein turnover in the human fetus studied a term using stable isotope tracer amino acids
However, taking higher-than-recommended doses for long periods is not advised
In summary, the core breakthrough in current HIF-targeted drug development lies in establishing the regulation of ROS generation (inhibiting pathological accumulation or controllably utilizing its killing effect) as the key hub for intervening in hypoxia-related diseases
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