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GSTO1 inhibition is cytotoxic to cancer cells We evaluated the expression of GSTO1 in various tumour types using publicly available gene expression data sets from the Oncomine database
Its consistent performance profile makes it suitable for ongoing research involving growth, recovery, and metabolic balance
The Gq/11 pathway activates phospholipase C (PLC), which hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) into IP3 and diacylglycerol (DAG)
It may also help increase levels of this important compound
By contrast, the serotonin metabolic pathway of Trp has been less extensively studied in macrophages
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