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A rather simple but very effective method of removing dominant epitopes to enhance responses to conserved subdominant epitopes involved the removal of the S1 portion of spike containing the RBD and then the administration of a vaccine with only S2 as a DNA vaccine or protein [73] (Table 2)

Veterinary Applications and Translational Insights Interestingly, both peptides have demonstrated therapeutic potential in veterinary applications, and clinical experience in animal medicine may provide valuable insights into safety and efficacy profiles

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