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A 19% combined reduction in kidney failure, worsening kidney function, and death due to kidney disease

Unlike the PAR2-G37I mutant, PAR2-R38E mice are insensitive to a wide range of proteases that may have homeostatic functions (21, 22)

Starting both simultaneously amplifies side effects from both approaches, including nausea, fatigue, constipation, and dizziness

The association between inflammation and chronic disease is still under investigation and how to translate the body of knowledge into effective strategies for the prevention and treatment of pathologic inflammation is lagging