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Bacterial growth likely if any contamination occurred during reconstitution or drawing doses
Additionally, because NAD+ supports metabolic pathways, some practitioners recommend taking a methyl donor supplement (such as TMG, trimethylglycine) concurrently, to aid in processing any excess nicotinamide produced
In addition, it is one of a few antihyperglycemic agents associated with improvements in cardiovascular morbidity and mortality, which is a major cause of death in patients with type 2 diabetes
A 2024 pilot study found that 7 of 12 patients with chronic knee pain reported relief lasting six or more months after BPC-157 treatment
It may also result in decreased bone density and muscle mass
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