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All participants provided informed consent, and participation was entirely voluntary

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This has led many patients and clinicians to explore comprehensive nutritional support designed to bypass these metabolic blockades

Melanocytes can also function as neuroendocrine cells by producing acetylcholine, catecholamines, and POMC-derived peptides, which have the capacity to mediate local immunoinflammatory and antimicrobial responses and to modulate the biological behaviour of oral tissues [4]