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The K305R mutation reduces the extracellular acidification rate (ECAR) and lactate production, and the proliferation activity of VSMC is weakened along with the inhibition of glycolysis
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Steiling H, Werner S
it also increases the risk of heart disease and type 2 diabetes
Experts classify GLP-1 receptor agonists into two types: human GLP-1 backbone agents (e.g., Liraglutide, Dulaglutide, Semaglutide) and exendin-4 backbone agents (e.g., exenatide) (23)
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