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Semaglutide, marketed as Ozempic, Wegovy, and Rybelsus, is an FDA-approved GLP-1 receptor agonist used for type 2 diabetes management and chronic weight management
Retatrutides 24.2% weight loss result comes from a 338-person Phase 2 trial with a relatively homogeneous population it cannot be directly compared to Tirzepatides 2,539-person Phase 3 SURMOUNT-1 data without acknowledging this statistical limitation
However, it is crucial to contextualise these findings
