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American College of Gastroenterology guideline: Management of acute pancreatitis

Astrocytes, key modulators of neuroinflammation, congregate around A plaques, as described in both human and mouse models

The most common side effects are gastrointestinal: nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite

Oral semaglutide for weight loss in non-diabetics is approved, meaning you don't need to have diabetes to be eligible

Similar concerns have been seen with lipid outcomes with an increase in total cholesterol after cessation of semaglutide to near pretreatment levels and loss of around two-thirds of the benefit in triglycerides, while positive changes in LDL-C and HDL-C were more modest but appeared more durable (Table 2) [73]