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One prominent mechanism is the downregulation of major histocompatibility complex class I (MHC-I) molecules on tumor cells, which impairs antigen presentation and reduces the visibility of malignant cells to cytotoxic T lymphocytes ( The expression of immune checkpoint molecules, including PD-L1, provides another layer of immune evasion
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Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis
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