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Speaking of cholesterol, another recent study found that there can be too much of a good thing

These synthetic analogs are also chemically modified to resist enzymatic degradation, allowing them to remain active in your bloodstream for hours to days rather than minutes

Immunofluorescence staining of cultured cells Cells were seeded 4 days pre-treatment on 13 mm coverslips cleaned with 70% EtOH and treated with PDL (0.08 g/mL) in 24-well plate

doi: 10.1038/nature18629 44 XiaoJWangLZhangBHouA

It is present in virtually all aerobic cells at millimolar concentrations where it takes part in numerous fundamental processes