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An ancestral glutamine-dependent NAD(+) synthetase revealed by poor kinetic synergism
Summary FOXO4-DRI is a pioneering senolytic peptide designed to selectively target and eliminate senescent cellsthose that have lost their ability to divide yet persist in a pro-inflammatory, dysfunctional state
S2CID 236219189
No saturation behavior for GSSG was previously detected for the fusion construct between rxYFP and ScGrx1 31 , which makes sense considering that PfGrx and many other glutaredoxins are at least two orders of magnitude more active than ScGrx1 (Table 1) 14,56
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