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Pharmacol Res (2002) 46(2):12931.10.1016/S1043-6618(02)00080-4 21 LongJDMatsonWRJuhlARLeavittBRPaulsenJSPREDICT-HD Investigators and Coordinators of the Huntington Study Group
Understanding these differences is important for making an informed treatment decision
In the future, we will develop small molecule inhibitors or activators for specific transporters such as SLC25A39 and xCT, and use gene editing tools (such as CRISPR/Cas9) to precisely edit related genes to achieve precise regulation of GSH metabolism, providing more targeted means for disease treatment
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