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Vuilleumier S
Isatuximab binds to the CD38 epitope via its gamma heavy chains, inducing cell death through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and apoptosis 146,147
Glutathione (GSH), a key regulator of oxidative stress and cellular immunity, has a critical role in modulating the functional states of CNS-resident and infiltrating immune cell subsets
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