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At these pH values, the peptide molecules carry minimal net charge, which reduces the electrostatic repulsion that normally keeps individual molecules separated

Lancet Lond Engl 390:16641675 DeFronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD (2005) Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes

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Blue dye combined with normal yellow-brown bile produces a striking green that alarms people more than the natural version