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The characteristics of non-healing wounds include long-term or excessive inflammation, persistent infection, microbial biofilm formation, and the incapacity of dermal or epidermal cells to react to repairing stimuli ( Hydrogels have been found to effectively improve wound healing and functional recovery (Zhang et al., 2020)
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Future investigations employing sequential single-cell transcriptomics, specific inducible gene knockouts, and clinical cohort stratification are urgently needed to elucidate these temporal dependencies, which will pave the way for precise, stage-targeted RCD-modulating therapies in DKD
That said, you may still want to manage expectations
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