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One ingredient gets crowned, the other gets dismissed, and readers walk away with a purchasing decision rather than an understanding
In silico approach confirms a reduction of late-INa by empagliflozin demonstrating that SGLT2 inhibitors may be the ligands for the cardiac sodium channel Nav1.5 isoform that drives late-INa (Philippaert et al., 2021)
Oral Investig
This isnt the first time the side effects of Ozempic and similar drugs which are used for weight loss as well as diabetes management have made headlines In July, the European Medicines Agency (EMA) broadened its probe into the manufacturer, Novo Nordisk, after reports from the Icelandic Medicines Agency found two cases of suicidal thoughts (potentially linked to Ozempic and Saxenda), and one case of thoughts of self-harm (linked to Saxenda), according to Reuters
For patients undergoing larger reconstructive procedures or combined surgeries under monitored anesthesia or general anesthesia, I defer to anesthesia colleagues about whether a temporary hold is necessary
