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Contraindications include active skin infections at treatment sites, known copper metabolism disorders, pregnancy and breastfeeding (for injectable applications), and severe allergic reactions to copper compounds

GLP-1 MODULATES LIPID METABOLISM GLP-1 Modulates fat synthesis in the liver GLP-1 modulates hepatic lipolysis GLP-1 modulates liver cholesterol metabolism GLP-1 modulates adiposynthetic and differentiation GLP-1 modulates fat browning Clinical application of GLP-1 in obesity Obesity is a major health problem worldwide

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and nephrogenic diabetes insipidus

Combining it with Insulin or Sulfonylureas may increase the risk of low blood sugar