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The Revolution in Obesity Treatment: Before GLP-1 Medications: Diet and exercise alone: 3-5% sustained weight loss Older medications: 3-7% weight loss Bariatric surgery: 15-30% weight loss Gap between medication and surgery After GLP-1 Medications: Semaglutide: 10-15% weight loss Tirzepatide: 15-22% weight loss Bridge the gap with non-surgical option Results rival some bariatric procedures GLP-1 therapy has fundamentally changed whats possible with medical weight loss treatment
Moreover, the activation of M1 microglia was also inhibited by semaglutide, which may be related to its protective effects
Some individuals (7% of those on Retatrutide compared to 1% on placebo) experienced skin sensitivity, but these cases were not serious
Patients who want to lose fat while protecting lean mass should work with a provider who builds muscle-preservation strategies into the plan from the beginning
It also stimulates insulin production, which helps manage blood sugar levels after meals
