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Caloric restriction during weight loss can temporarily affect thyroid hormone levels , which may contribute to cold sensitivity without representing true hypothyroidism
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As David Moore, executive vice president of Novo Nordisks U.S
It occurs at the level of gene transcription [11, 12], epigenetic regulation [13,14,15], post-translational modifications of core and accessory cell death machinery components [16,17,18], organelle-specific mechanisms [19], and organelle crosstalk [20, 21]
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