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In a 2025 review, after 1,200 mg intravenously twice a week for six weeks, 37.5% of participants reported lighter skin compared with 18.7% in the placebo group, and the effect faded after about six months
Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide
doi: 10.1038/s41467-021-22938-y 100 ZhaoLZhangFDingXWuGLamYYWangXet al
It cannot remove excess loose skin, but it can help improve how skin feels and appears with consistent use
Most patients start with the lowest available dose to minimize side effects and allow the body to gradually adapt to the medication
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