Individuals experiencing low energy levels or chronic fatigue
According to Kaplan-Meier plots, patients with elevated levels of MMA had significantly increased cumulative incidence of cardiovascular and heart-specific death (Supplementary Fig
Medications use, including cardiovascular prescriptions ACEI/ARB, -blocker, diuretics, anti-lipid agents, and anti-platelet agents, and Metformin, during the 30 days prior to the interview was ascertained from self-report [20]
Spinal cord damage Spinal cord damage, known as myelopathy (problem with the spinal cord), is also associated with vitamin B12 deficiency
Diabetics who take metformin may have low B12 levels as a side effect of the drug