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Clinically, the first sign of deficiency is anemia

According to Professor Adrian R Martineau, 1 March 2015, in his article discussing the main recommendations for healthcare practitioners in NICE Public Health (PH) guidance 56 on Vitamin D: increasing supplement use among at-risk groups: "Health professionals do not need to routinely test vitamin D status in asymptomatic people in at-risk groups before advising them to take a vitamin D supplement

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These symptoms often correlate with other gastrointestinal effects and may be particularly noticeable after meals due to delayed gastric emptying