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According to the Mayo Clinic, if your vitamin deficiency is severe enough to make you feel lethargic, you could gain weight as a result of reducing your exercise and movement

Further, NASO B12 was well-tolerated throughout the treatment period.[] Patients on metformin therapy receiving NASO B12 should also be instructed that they will require weekly intranasal administration of NASO B12 spray in each nostril after correction of vitamin B12 deficiency for the remainder of their lives

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