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A meta-analysis showed that GLP-1RAs could increase lean body mass, cross-sectional area of muscle fibers and grip strength in animal models, enhance the expression of muscle growth factors, and inhibit genes related to muscle atrophy and inflammatory factors [62]
More recent work (Sosa-Hernandez et al., 2024) showed it prevented doxorubicin-induced organ damage by attenuating oxidative stress and supporting mitochondrial integrity
Marettova E, Maretta M, Legath J
Mitochondrial function slows as oxidative damage accumulates
Always discuss persistent symptoms with your GP rather than stopping medication independently
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