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The Sonic hedgehog signaling pathway is activated in pancreatic tumor CSCs, and sanguinarine has been shown to play a role in the secondary pathway, while sanguinarine upregulates E-cadherin and inhibits N-cadherin to inhibit the EMT process and prevent pancreatic cancer progression
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(PubMed) Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT
Folic acid handling by the human gut: implications for food fortification and supplementation
Kishi T, Rider LG, Pak K, Barillas-Arias L, Henrickson M, McCarthy PL, Shaham B, Weiss PF, Horkayne-Szakaly I, Targoff IN, Miller FW, Mammen AL (2017) Association of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies with DRB1*07:01 and severe myositis in juvenile myositis patients
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