Required evidence may include clinical studies, extensive post-marketing use data, expert advice, and the views of relevant health professionals and public associations
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Because almost all controlled research to date has been conducted in rodent models, intellectual honesty requires treating the human implications as promising extrapolations rather than established clinical fact
In reality, treatment often begins with conservative strategies aimed at improving function, reducing pain, and maintaining mobility for as long as possible
Doctors can just as easily be blind to it in people even though B12 deficiency is a common health problem that affects an estimated 6% to 20% of the U.S