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REDEFINE 1 Combination Data The closest analog for layered amylin + incretin tolerability is REDEFINE 1, where cagrilintide 2.4 mg was paired with semaglutide 2.4 mg: The pattern: layering cagrilintide on a GLP-1 backbone produced modestly more GI events than the GLP-1 alone, but discontinuation rates were similar
It may also be inconsistent, and only be effective on some parts of the body
The cancer caution matters most
Waking up choking on acid at 3 AM
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