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If GHK-Cu penetrates poorly through intact skin, the observed clinical effects could be occurring primarily at the epidermal level rather than reaching dermal fibroblasts where collagen synthesis occurs

Typically those results last about 1 to 2 years

The 2024 Redox Biology lung-inflammation paper (PMID 38879894) and the 2026 European Journal of Pharmacology anti-inflammatory paper (PMID 41997403) extend the redox-pathway work into respiratory-research model systems

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