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However, despite the good pharmacological properties shown by this molecule on several cancers, its use in the clinic is problematic because of its strong diuretic properties

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thus, depleted levels of Myo may cause the pathogenesis of thyroid diseases such as hypothyroidism (187)

If efficacy favors tretinoin, tolerance decisively favors GHK-Cu and for many people, tolerance is what determines whether a product is actually used long enough to work

Additionally, it is a challenge to have a major impact on glutathione levels from food because much of it is broken down in the gut