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As an FDA-approved weight loss medication, it is used to treat type 2 diabetes and control blood sugar levels, as well as reduce excess weight in patients with obesity
In the meantime, mitochondrial dysfunction is induced by hepatic IR and lipid accumulation and the lipid peroxidation mediated by cytochrome p450 2E1 boost the production of reactive oxygen and promote the degradation of mitochondria (125), which could further lead to the lack of cellular energy and metabolic intermediates accumulation, all these may lead to the secretion of pro-inflammatory cytokines, hepatocellular apoptosis and hepatic fibrogenesis, finally resulting in cirrhosis of the liver (125) ( Figure 3 )
Retrieved from Fujiwara, Y., Machida, A., Watanabe, Y., et al
To ensure safe and effective treatment, it's crucial to have open communication with your healthcare provider, providing them with a comprehensive understanding of your medical history and current medications
The popular weight-loss drugs known as GLP-1 receptor agonists, which were originally meant to treat diabetes, surged in popularity after the Food and Drug Administration approved them for weight loss in 2021
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