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While animal studies consistently demonstrate beneficial effects across diverse injury models and tissue types, the absence of adequately powered, controlled human clinical trials prevents definitive conclusions about efficacy in human disease
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Rutin protects against cyclophosphamide induced immunological stress by inhibiting TLR4-NF- B-mediated inflammation and activating the Nrf2-mediated antioxidant responses
Schmitz TW, Spreng RN, Initi AsDN
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