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The first step is rate-limiting and subject to feedback inhibition by glutathione itself, holding intracellular concentrations in the low millimolar range, typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999
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Mitochondria in the cold
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Kobayashi S, Sato M, Kasakoshi T, Tsutsui T, Sugimoto M, Osaki M et al (2015) Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function
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