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Hepatology 70 , 21A22A (2019)

In addition, we have specifically targeted and blocked the pivotal elements responsible for the EA effect, the GLP-1 neurons and the afferent fibers of the vagus nerve, and found that the effect of EA is partially antagonized

Appears to modulate gene expression related to vascularization and nitric oxide signaling, suggesting potential benefits for blood flow and antioxidant activity8

First pass effect describes metabolism of a drug that occurs Sites of First-Pass Metabolism The blood vessels draining the stomach and intestines do not lead directly to the general circulation

Limitations of Use: Foundayo should not be used in combination with other GLP-1 receptor agonists