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When used for medical purposes alone, they could affect 20% of US adults 50 million people

P 80% stayed on SGLT2i for the trial duration (Extended Data Fig

What to expect if you overeat: Increased fullness: You may feel uncomfortably full for longer than usual Nausea: Some people experience increased nausea after overeating Bloating: The slower digestion can increase feelings of bloating Heartburn: Some people report more acid reflux when overeating on Wegovy What to do if youve overeaten: Dont panic or feel guilty, occasional overeating happens to everyone Stay hydrated with water (avoid carbonated drinks which can increase bloating) Consider a gentle walk to help with digestion Return to your normal eating pattern at the next meal Use it as a learning experience about your new fullness signals and adapt your portion size for next time If you find yourself regularly overeating despite physical discomfort, it may be worth exploring the emotional aspects of your eating patterns

Testing & Evaluation Complete the recommended lab work, imaging, or specialty testing based on your assessment

And do not ignore signs that symptoms are worsening