However, as reassuring as all of this is, there are a couple of things to remain mindful of: Copper toxicity Because GHK-Cu contains copper, it does pose a potential risk of copper toxicity,12 the symptoms of which include abdominal pain, vomiting, chest pain, chills, cough, fever, general weakness, anemia, burning sensations, tremors, and a metallic taste in the mouth.13 The risk is small, as the concentrations of copper in the peptide are typically well within safe parameters, but its good to be aware of it
the larger the number, the greater the improvement
Overall, the trial demonstrated that once-weekly Cagrilintide induced clinically meaningful, dose-dependent weight loss in adults with overweight or obesity, with efficacy comparable or superior to liraglutide 3.0 mg
Works well alongside: Hyaluronic acid Niacinamide Ceramides Gentle moisturizers and lipid-based moisturizers Daily SPF (non-negotiable) Microneedling LED therapy Chemical peels (during the healing phase, not the same day as the peel) Keep separate from: Vitamin C AHAs and BHAs High-strength retinoids The simplest workaround is to alternate
PMID 40005999