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PI3K then produce phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which recruits and activates Akt (protein kinase B)
Briefly, 96-well ELISA microplates were coated with HGFR/c-MET Fc chimera (50 ng/well), blocked with 1% BSA, 5% sucrose, and 0.05% sodium azide in PBS, and then incubated for 2 h at 37C with HGF samples
The anti-inflammatory effects of GLP-1 drugs are particularly promising in this context
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