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J Biol Chem 279:4782247832 Huang HH, Lin LH, Zhang P, Qi XL, Zhong DF (2006) Formation of glucoside conjugate of acetaminophen by fungi separated from soil

Acid keeps the protein away from the pH at which its net charge is lowest and aggregation is most favorable, but it also means the concentrated stock is not at physiological pH and that transferring it into a buffered medium involves a pH transition where local precipitation can occur if it is done abruptly into a small volume

Because theyre naturally occurring, peptides are well-tolerated , highly targeted , and minimally invasive making them one of the most promising therapies in modern functional and regenerative medicine

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