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For decades, treatment of urea cycle disorders has consisted of nitrogen scavengers, dietary protein restriction, arginine or citrulline supplementation, calorie support, and liver transplant

This age-associated carnitine depletion contributes to mitochondrial dysfunction, reduced physical capacity, and metabolic inflexibility

In sport, it is usually considered as part of a global approach that includes training and nutrition, such as strategies to maintain muscle mass , and it is always advisable to adjust expectations

Food raises insulin, and insulin blunts the GH pulse

BVAS: the Birmingham vasculitis activity score