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doi: 10.3389/fbioe.2025.1729166 Received 21 October 2025 Revised 01 December 2025 Accepted 17 December 2025 Published 15 January 2026 Volume 13 - 2025 Edited by Ling Wang, Dalian Medical University, China Reviewed by Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Updates Copyright 2026 Hu, Li, Hu, Shan, Tang, Jiang, Yi, Chen, Jin, Wang and Wang
Its mechanism of action is based on mimicking the natural hormone GLP-1 (glucagon-like peptide-1), which plays a role in regulating appetite and blood glucose
Some use sophisticated formulation strategies with multiple stabilizing excipients
In addition, there seems to be evidence for sex-specific responses to polyphenols in the context of ES
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