glp 1 type 1 diabetes SGLT2i and GLP-1 RA therapy in and reno-vascular outcomes: a real-world study | Diabetologia GLP-1-based therapies for diabetes, obesity

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Rats receiving brainstem-hypothalamic transection do not have a reduction in food intake in response to peripherally administered GLP-1 which suggests that the brainstem plays a critical role in communicating peripheral satiety signals to higher brain centers (Abbott et al., 2011)

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This explained why dTTP pool is particularly higher in these cells