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In a model of complete Achilles tendon transection in rats (Staresinic et al., 2003), BPC-157 administration resulted in significantly superior functional recovery compared to the control group, with improved collagen fiber organization on histological analysis
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The alcohol, carbonyl and antioxidant functional groups could still be attributed to the flavonoids and phenolics which possess a strong affinity to bind metal ions and may be encapsulated around the nanoparticles, forming a protective coat-like membrane preventing the agglomeration and thus resulting in nanoparticle stabilization in the medium [21]
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