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No, Glutathione is not thought to significantly increase your weight in any way

Glutathione S-transferase detoxication enzymes in cervical neoplasia

Tran MT, Doan DTH, Kim J, Song YJ, Sung YW, Das S, et al

GHK-Cu exerts broad anti-inflammatory effects through its influence on approximately 31% of the human genome, specifically downregulating genes involved in inflammatory processes including interleukin-1, tumor necrosis factor-, and nuclear factor-B (NF-B) signaling while upregulating protective genes encoding antioxidant enzymes, DNA repair proteins, and anti-inflammatory mediators

The frequency of B12 injections can vary based on individual needs, current B12 levels, and specific health goals