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MK-677 is contraindicated in subjects with a history of cancer or active malignancies, as increased GH and IGF-1 levels can stimulate the proliferation of cancer cells and disease progression
doi: 10.1016/j.jsbmb.2008.03.027 144 QureshiRPicon-RuizMAurrekoetxea-RodriguezINunes de PaivaVDAmicoMYoonHet al
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