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review your medication's prescribing information with your licensed healthcare provider Key research context: A 2024 phase 2 RCT documented 2.6% hip and 2.1% lumbar spine BMD reduction in a specific semaglutide study population within 52 weeks
The frequency of dose stays consistent: one shot per week, administered either with or without food on the same day each week
As for nootropic/pre-workout purposes, it has more promise
References Chang CH, Chen CH, Su CY, et al
[36] [37] In January 2026, the US Food and Drug Administration requested removal of a suicidal behavior and ideation warning from GLP-1 receptor agonist medications
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